Association of TBX21 gene polymorphism with nasal polyposis
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولTNF-α and IL-1 β Cytokine Gene Polymorphism in Patients with Nasal Polyposis.
Objective Nasal Polyp (NP) is a benign mass of the paranasal sinuses that protrudes into the nasal cavity. The exact underlying pathogenesis is not known. In this study we aimed to determine the genetic susceptibility of NP formation in relation to TNF-α-308 and IL-1β-511 promoter region gene polymorphisms. Methods A total of 71 patients with NP with asthma (n=21) or without asthma (n=50) wer...
متن کاملAssociation between the functional polymorphism C-159T in the CD14 promoter gene and nasal polyposis: potential role in asthma.
BACKGROUND Nasal polyposis (NP) is a chronic inflammatory disease that is frequently associated with allergy and asthma. Corticosteroid therapy and surgical removal of polyps are the 2 most common treatment strategies for NP. Various allergic and inflammatory mediators are thought to play a major role in the pathophysiology of this disorder. The CD14 gene is located on chromosome 5q31-32, which...
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Nuclear genetic mutations have been extensively investigated in solid tumors. However, the role of the mitochondrial genome remains uncertain. Since the metabolism of solid tumors is associated with aerobic glycolysis and high lactate production, tumors may have mitochondrial dysfunctions. Familial adenomatous polyposis (FAP) is a rare form of colorectal cancer and an autosomal dominant inheri...
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Urokinase might play a role in the formation of kidney stones. This study was done to determine the association between +4065 T/C polymorphism at the 3′-untranslated region of urokinase gene and calcium kidney stones. This Case-Control study was carried out on 70 cases with a history of calcium kidney stones and 70 controls from the Baqiyatallah hospital of Tehran in 2013. The study of polymorp...
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ژورنال
عنوان ژورنال: Praxis of Otorhinolaryngology
سال: 2019
ISSN: 2587-0408
DOI: 10.5606/kbbu.2019.16056